How MicroRNAs Could Change Early Detection of Alzheimer’s Disease

How MicroRNAs Could Change Early Detection of Alzheimer’s Disease

51:14 Apr 1, 2026
About this episode
In this episode of Research Renaissance, host Deborah Westphal sits down with neuroscientist Micaelly Alves, PhD candidate at Temple University and a 2025 Toffler Scholar supported by the Karen Toffler Charitable Trust.Micaelly shares her personal journey into neuroscience, inspired by watching her grandmother’s battle with Alzheimer’s disease, and dives into groundbreaking research on microRNAs, tiny molecules that may hold the key to earlier diagnosis and more personalized treatment for Alzheimer’s and cerebral amyloid angiopathy.The conversation explores how brain research is evolving, why personalized medicine matters, and how emerging technologies like RNA sequencing and bioinformatics are accelerating discovery.⭐ Key Takeaways• How microRNAs regulate brain pathways linked to Alzheimer’s disease• Why Alzheimer’s may begin developing 20 years before symptoms appear• The role of blood-brain barrier health in cognitive decline• How extracellular vesicles may enable early blood-based diagnostics• Why personalized medicine is the future of neurological care• The challenges and promise of big data and AI in neuroscience• How philanthropy supports early-career researchers and innovation🔬 Resources & Mentions• Temple University Neuroscience Program• MicroRNA research in Alzheimer’s disease• Cerebral amyloid angiopathy (CAA)• RNA sequencing and transcriptomics👉 Enjoying Research Renaissance?If you found this episode helpful:✅ Subscribe on Apple Podcasts or Spotify✅ Share this episode with a friend or colleague✅ Leave a review to help more listeners discover the showTo learn more about the breakthroughs discussed in this episode and to support ongoing research, visit our website at tofflertrust.org. Technical Podcast Support by Jon Keur at Wayfare Recording Co.
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