A Better U: How Psychedelic Therapy Changed One Life—and Launched a Movement
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A Better U: How Psychedelic Therapy Changed One Life—and Launched a Movement

29:13 Aug 21, 2025
About this episode
In this emotional and eye-opening episode of What It Takes: Business Owners Tell All, host Jamie Seeker sits down with Derek Du Chesne, co-founder and CEO of Better U, a telehealth company offering at-home psychedelic therapy. Derek shares his deeply personal journey—from achieving outward success to hitting rock bottom after a mental health crisis. He opens up about how a single ketamine therapy session saved his life, shifted his inner dialogue, and inspired him to start a mission-driven company focused on making mental health treatment more accessible, affordable, and holistic.Listeners will hear firsthand about Derek’s transformation, how Better U was born, and why he's committed to disrupting the current mental health care model. The conversation offers hope, insight, and a candid look at what it really takes to create something that matters.? Show Notes / Key Moments & Takeaways? Derek’s Mental Health CrisisAt the height of career success in cannabis and wellness industries, Derek faced a personal collapse: career severance, heartbreak, and deep depression.Despite financial security, he felt empty and experienced suicidal ideation.Traditional therapies (psychiatric meds, talk therapy, even seeing a shaman) weren’t helping.? Ketamine Therapy as a Turning PointA friend intervened during Derek’s lowest point and introduced him to ketamine therapy.After one session, he experienced a profound mental “reset.”He describes the experience as the first time in months he could breathe and feel connected again.? The Birth of Better UInspired by his transformation and time spent with psychedelic researchers at Stanford, Derek felt a responsibility to help others.Noted barriers to ketamine therapy: stigma, cost ($1,500/session), and lack of aftercare.Launched Better U in 2021 with Dr. Sam Zand to offer more affordable, supported, at-home treatments.?? Building a Scalable Mental Health PlatformBetter U has now delivered 200,000+ sessions across 35 states.Leveraged telehealth innovations post-pandemic to offer oral ketamine therapy safely at home.Reduced cost to ~$100 per session—making it 10x more accessible.???? A Holistic Approach to HealingBetter U now offers a broader platform including:Ketamine-assisted therapyFunctional medicineWeight loss programsSexual healthHolistic psychiatry & soon, talk therapyFocused on helping patients find multiple tools for healing—not just a single pill.? Derek’s “What It Takes” Insight“Relentless commitment to t
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