About this episode
Hello Wise Wordians,Welcome back to another episode of ‘Wise Words Book Summaries’.This week we are summarising ‘Metabolical’ by Robert Lustig which explores the relationship between processed foods and its overwhelming consequences on our health. In this episode, we cover topics such as:Debunking ‘Chronic Disease”The Eight Sub-cellular PathwaysPathways that are Foodable, Not DruggableWhat Does “Healthy” Really Mean?The Nutrition MythologyPharmacokinetics and PharmacodynamicsIf any of these topics sound interesting to you then make sure to give it a listen, and if you enjoy what you hear, why not leave us a like, subscribe to our channel, or even better, let us know your thoughts in the comment section below, your feedback means so much to us and helps to improve our podcast.In addition, if you fancy implementing any of the actionable ideas we mention in this episode, head over to our website at wisewords.blog where the ‘Metabolical’ book summary will be waiting for you.Next week we will summarise the last section of ‘Metabolical’ so stay tuned.We hope you enjoy it.------------------Chapter:00:00:00-Intro00:01:01-Part II-Debunking ‘Chronic Disease”00:01:25-The “Diseases” That Aren’t Diseases00:06:53-Eight Sub-cellular Pathways00:07:04-1. Glycation00:07:42-2. Oxidative Stress00:10:30-3. Mitochondrial Dysfunction00:15:33-4. Insulin Resistance00:18:19-5. Membrane Integrity00:21:51-6. Inflammation00:28:05-7. Epigenetics00:40:00-8. Autophagy00:42:37-Checkpoints Alpha, Bravo, Charlie: Nutrient-Sensing and Chronic Disease00:43:02-Oxygen Is So Overrated00:44:54-Two Metabolic Programs—One for Growth, One for Burning00:48:41-Checkpoint Alpha: Phosphatidylinositol-3-kinase (PI3-kinase)00:50:04-Checkpoint Bravo: Adenosine Monophosphate-kinase (AMP-kinase)00:52:01-Checkpoint Charlie: Mammalian Target of Rapamycin (mTOR)00:55:37-Foodable, Not Druggable01:06:02-Diabetes—the Modern Scourge01:11:59-Part III Notes from the Nutritional Battlefield-What Does “Healthy” Really Mean?01:17:58-Nutrition mythology01:24:26-Roberts Definition of “Healthy”01:32:23-Nutrition “Unwrapped”01:39:03-Pharmacokinetics and Pharmacodynamics01:42:44-A Fibre Is Not a Fibre01:47:28-A Carb Is Not a Carb01:50:45-Carbs and Glycemic Index (GI)01:54:34-A Protein Is Not a Protein01:58:28-What and How Adults Eat01:58:57-Here are why supplements can't help the 8 subcellular pathways02:01:41-How to repopulate your unhappy gut:02:02:55-What and How Children and Adolescents Eat02:03:23-Breakfast Is a Dangerous Meal02:04:43-Fructose Effects on the Brain02:09:10-DebriefIf you enjoyed this podcast make sure to check out ou